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Phase II Tosedostat trials in blood cancer resume
January 2, 2014
By: Kristin Brooks
Managing Editor, Contract Pharma
Cell Therapeutics, Inc. has received notification from FDA lifting the partial clinical hold on tosedostat (IND 075503), allowing all studies to continue. Tosedostat, a selective inhibitor of aminopeptidases, which are necessary for growth and tumor cell survival, is under development for the treatment of blood-related cancers. Tosedostat is currently being studied in Phase II trials in elderly patients with newly diagnosed and relapsed acute myeloid leukemia (AML) and high-risk myelodysplastic ...
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